Oprah Winfrey reflects on the distance she has traveled and the perspective that came with it. In conversation with Jane Pauley, she looks back on her early career in local television, the obstacles she faced and what matters most to her now. | CBS Sunday Morning

Oprah Winfrey is one of the best-known, most-admired and successful people on the planet. After decades of public struggle with her weight, new medications and a new understanding of her body led to a breakthrough she describes in “Enough,” a book she co-wrote with Dr. Ania Jastreboff. Winfrey speaks with Jane Pauley about genetically influenced weight ranges, how they can be reset and why reframing weight as a medical issue — not a personal failure — changed everything. | CBS Sunday Morning